Darkseid isn't satisfied with only ruling Apokolips. He seeks to obtain the Anti-Life Equation, which would allow him to destroy free will and bind all living beings to him. Despite his immense power and far-reaching goals, Darkseid has had many setbacks, including some truly humiliating defeats.
When Aquaman, The Flash, and Green Lantern ended up in a future where Darkseid ruled the Earth, they needed that era's JLA to help them get back to their time. As Darkseid closed in on them, he defeated Wonder Woman and bragged about his impenetrable force-field to Batman before killing him.
Howevrer, the Atom realized that light could pass through Darkseid's protective shield, so he shrunk himself to the size of a photon and rode the light waves of Green Arrow's flare arrow straight through Darkseid's eye and up his optic nerve into his brain. From there, Earth's tiniest hero used his suit's on-board weaponry to fry the Lord of Apokalips's brain, killing him in that timeline.